Computation of Electromagnetic Fields in Assemblages of Biological Cells Using a Modified Finite-Difference Time-Domain Scheme
See, C H, Abd-Alhameed, R A and Excell, Peter S (2007) Computation of Electromagnetic Fields in Assemblages of Biological Cells Using a Modified Finite-Difference Time-Domain Scheme.
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Abstract
When modeling objects that are small compared with the wavelength, e.g., biological cells at radio frequencies, the standard finite-difference time-domain (FDTD) method requires extremely small time-step sizes, which may lead to excessive computation times. The problem can be overcome by implementing a quasi-static approximate version of FDTD based on transferring the working frequency to a higher frequency and scaling back to the frequency of interest after the field has been computed. An approach to modeling and analysis of biological cells, incorporating a generic lumped-element membrane model, is presented here. Since the external medium of the biological cell is lossy material, a modified Berenger absorbing boundary condition is used to truncate the computation grid. Linear assemblages of cells are investigated and then Floquet periodic boundary conditions are imposed to imitate the effect of periodic replication of the assemblages. Thus, the analysis of a large structure of cells is made more computationally efficient than the modeling of the entire structure. The total fields of the simulated structures are shown to give reasonable and stable results at 900,1800, and 2450 MHz. This method will facilitate deeper investigation of the phenomena in the interaction between electromagnetic fields and biological systems.
| Item Type: | Article |
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| Additional Information: | ©2007 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE. This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.The paper was published by IEEE Transactions on Microwave Theory and Techniques in 2007 and the definitive version is available at http://dx.doi.org/10.1109/TMTT.2007.904064 |
| Keywords: | generic lumped-element membrane, quasi-static, floquet periodic, electromagnetic fields, biological systemsmicrodosimetric modeling, bioelectromagnetic interactions, verisimilitude, electromagnetic fields, assemblages |
| Divisions: | ?? GlyndwrUniversity ?? |
| Depositing User: | ULCC Admin |
| Date Deposited: | 05 Oct 2011 09:13 |
| Last Modified: | 11 Dec 2017 20:06 |
| URI: | https://glyndwr.repository.guildhe.ac.uk/id/eprint/189 |
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