Electrostatic interaction-based fabrication of calcium alginate–zein core–shell microcapsules of regulable shapes and sizes

Zhang, Xun, Hu, Bing, Zhao, Yiguo, Yang, Yisu, Gao, Zhiming, Nishinari, Katsuyoshi, Yang, Jixin, Zhang, Yin and Fang, Yapeng (2021) Electrostatic interaction-based fabrication of calcium alginate–zein core–shell microcapsules of regulable shapes and sizes. Langmuir, 37 (35). pp. 10424-10432. ISSN 1520-5827

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Abstract

Core–shell microcapsules with combined features of hydrophilicity and hydrophobicity have become much popular. However, the assembly of biocompatible and edible materials in hydrophilic–hydrophobic core–shell microcapsules is not easy. In this work, based on electrostatic interactions, we prepared controllable calcium alginate (ALG)–zein core–shell particles of different shapes and sizes using hydrophilic ALG and hydrophobic zein by a two-step extrusion method. Negatively charged hydrogel beads of spherical, ellipsoidal, or fibrous shape were added into a positively charged zein solution (dissolved in 70% (v/v) aqueous ethanol solution) to achieve different-shaped core–shell particles. Interestingly, the size, shape, and shell thickness of the particles can be regulated by the needle diameter, stirring speed, and zein concentration. Moreover, for simplification, the core–shell particles were also synthesized by a one-step extrusion method, in which an ALG solution was added dropwise into a 70% (v/v) aqueous ethanol solution containing zein and CaCl2. The particles synthesized in this work showed controlled digestion of encapsulated medium-chain triglyceride (MCT) and sustained release of encapsulated thiamine and ethyl maltol. Our preparation method is simplistic and can be extended to fabricate a variety of hydrophilic and hydrophobic core–shell structures to encapsulate a broad spectrum of materials.

Item Type: Article
Keywords: Core−shell microcapsules Hydrogel beads Encapsulation Emulsion
Divisions: Applied Science, Computing and Engineering
Depositing User: Hayley Dennis
Date Deposited: 15 Sep 2021 14:53
Last Modified: 15 Sep 2021 14:53
URI: https://glyndwr.repository.guildhe.ac.uk/id/eprint/17812

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