Stereochemical rearrangements in tricarbonylrhenium(I) halide complexes of the non-racemic chiral ligand 2-[(4R),(5R)-dimethyl-1,3-dioxan-2-yl]pyridine (L): a dynamic NMR study

Heard, Peter J, Bain, Alex D and Hazendonk, Paul (1999) Stereochemical rearrangements in tricarbonylrhenium(I) halide complexes of the non-racemic chiral ligand 2-[(4R),(5R)-dimethyl-1,3-dioxan-2-yl]pyridine (L): a dynamic NMR study.

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Abstract

Tricarbonylrhenium(I) halide complexes of the non-racemic chiral ligand 2-[(4R),(5R)-dimethyl-1,3-dioxan-2-yl]pyridine (L), namely fac-[ReX(CO)3L] (X = Cl, Br or I), have been prepared and their latent fluxionality studied by dynamic NMR techniques in the slow and intermediate exchange regimes. In solution, these complexes give rise to four diastereoisomers, depending on the configuration at the metal and at the acetal-carbon atom, respectively; the relative populations are in the order SR > RR >> RS > SS. At moderate temperatures, a reversible ‘acetal ring flip’ leads to formal inversion of configuration at the acetal-carbon atom; the free energies of activation are in the range 84 - 88 kJ mol-1 at 298 K. Above ca. 370 K, reversible ligand dissociation also occurs, leading to an exchange of all four diastereoisomers on the NMR chemical shift time-scale.

Item Type: Article
Additional Information: Copyright © 1999, NRC Research Press or its licensors and the authors. This is the author's final version of the work after peer review. The article was originally published in Canadian Journal of Chemistry in 1999 by National Research Council Canada Press and the published version is available at http://www.nrcresearchpress.com/toc/cjc/77/11
Keywords: Tricarbonylrhenium(I) complexes, Dynamic NMR, Acetal complexes
Divisions: ?? GlyndwrUniversity ??
Depositing User: ULCC Admin
Date Deposited: 05 Oct 2011 09:14
Last Modified: 11 Dec 2017 20:07
URI: http://glyndwr.repository.guildhe.ac.uk/id/eprint/368

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